BLAME! Volume 5 features story and art by Tsutomu Nihei.

Davine Lu is attempting to access the Netsphere within an unofficial stratum of the megastructure, where temporary access can be granted even without a Net Terminal Gene. After a fierce battle, Pcell steals Cibo's precious capsule of human genetic information and forwards it to Davine Lu. After reuniting with Kyrii, Cibo and the provisional Safeguards try to retrieve the capsule before it's too late. As Davine Lu attempts to connect to the Netsphere, the Administration slows down his connection speed to allow Cibo to give virtual chase and for Dhomochevsky to battle the Silicon Life in base reality. As a final act, Davine Lu steals high-level data and uses Cibo's body to create an unstoppable Level 9 Safeguard...