BLAME! Volume 6 features story and art by Tsutomu Nihei.

In this final installment, Kyrii, still searching for the Net Terminal Gene, traces the steps of Cibo, reincarnated as a Level 9 Safeguard, and Sanakan, now a representative of the Administration. As Sanakan guides Cibo to a safe place where her sphere can develop in peace, Cibo is captured by the Silicon Life. Sanakan contacts Kyrii requesting his help in rescuing Cibo, because in her current form she may hold the key to saving the city. Sanakan risks everything in the battle against the Silicon Life. Kyrii arrives at a critical moment, and continues his endless journey while carrying the embodiment of hope for a different future beyond the outer limits of the city…