Colette Decides to Die manga volume 1 features story and art by Alto Yukimura.

When exhausted workaholic apothecary Colette jumps into a well, instead of dying she finds herself caring for a new patient: Hades, Lord of the Dead. As Colette goes back and forth between her world and the underworld, new patients of every kind arrive daily!

Colette meets Hades, a fellow workaholic, while he is ill in bed with a rash and fever. After treating his condition, she learns about the work he does and what drives him, which renews her sense of purpose as an apothecary. When Colette is sent back to her own world, is it the last she will see of Hades?